Michael Smith

Michael Smith
Beatha
Breith	Blackpool (en) , 26 dhen Ghiblean 1932
Dùthaich	Canada
Bàs	Vancouver, 4 dhen Dàmhair 2000
Foghlam
Foghlam	Oilthigh Mhanchester Arnold School (en)
Teusas	Studies in the stereochemistry of diols and their derivatives
Cànain	Beurla
Dreuchd
Dreuchd	ceimigear, bith-cheimigear, neach-teagaisg oilthigh agus eòlaiche-gintinneachd
Fastaichean	Oilthigh British Columbia
Duaisean a fhuaras	liosta Ball den Chomann Rìoghail Duais Nobel ann an Ceimigeachd  (1993) Companion of the Order of Canada Canada Gairdner International Award  (1986) Flavelle Medal  (1992) Canadian Medical Hall of Fame  (1995) honorary doctorate at the Laval University  (1995)
Ballrachd	An Comann Rìoghail Buidheann Eòrpach a' Bhith-eòlais Mhoileciuilich Acadamh Nàiseanta nan Saidheans
Creideamh
Creideamh	neo-dhiadhaireachd

B’ e ceimigear à Canada a bha ann am Michael Smith CC, OBC, PhD, LLD (Blackpool 26 an Giblean 1932–Vancouver 4 an Dàmhair 2000). Bhuannaich e an Duais Nobel ann an Ceimigeachd ann an 1993, còmhla ri Kary B. Mullis. Bha e ag obair ann an Oilthigh Columbia Breatannach ann an Canada bho 1956 gum bàs aige ann an 2000.

Aistean

• Ferrer, J.C., Turano, P., Banci, L., Bertini, I., Morris, I.K., Smith, K.M., Smith, M., Mauk, A.G. (1994). Active site coordination chemistry of the cytochrome c peroxidase Asp235Ala variant: Spectroscopic and functional characterization. Biochem. 33: (25) 7819-7829.
• Guillemette, J.G., Barker, P.D., Eltis, L.D., Lo, T.P., Smith, M., Brayer, G.D., Mauk, A.G. (1994). Analysis of the biomolecular reducation of ferricytochrome c by ferrocytochrome b5 through mutagenesis and molecular modelling. Biochimie 76: 592-604.
• Berghuis, A.M., Guillemette, J.G., Smith, M., and Brayer, G.D. (1994). Mutation of tyrosine-67 to phenylamaine in cytochrome c significantly alters the local heme environment. J. Mol. Biol. 235: 1326-1341.
• Rafferty, S.P., Guillemette, J.G., Smith, M., and Mauk, A.G. (1996). Azide binding and active site dynamics of position-82 variants of ferricytochrome c. Inorg. Chem. Acta.242: 171-177.
• Woods, A.C., Guillemette, J.G., Parraish, J.C., Smith, M., Wallace, C.J.A. (1996). Synergy in Protein Engineering. Mutagenic manipulation of protein structure to simplify semisynthesis. J. Biol. Chem. 271: (50) 32008-32015.
• Hildebrand, D.P., Ferrer, J.C., Tang, H.-L., Smith, M., and Mauk, A.G. (1996). Trans effects on cysteine ligation in the proximal His93Cys variant of horse heart myoglobin. Biocchemistry 34: 11598-11605.
• Hildebrand, D.P., Ferrer, J.C., Tang, H.-L., Luo, Y., Hunter, C.L., Brayer, G.D., Smith, M. and Mauk, A.G. (1996). Efficient coupled oxidation of heme by an active site variant of horse heart myoglobin. J. Am. Chem. Soc. 118: (51) 12909-12915.
• Maurus, R., Overall, C.M., Bogumil, R., Luo, Y., Mauk, A.G., Smith, M., and Brayer, G.D. (1997). Thermal stabilization of horse heart myoglobin through modification of a hydrophobic cluster in the proximal heme pocket. Biochem. Acta. 1341: 1-13.

Iomraidhean

Duais Nobel ann an Ceimigeachd